Disulfide Bond Formation and N-Glycosylation Modulate Protein-Protein Interactions in GPI-Transamidase (GPIT)

Glycosylphosphatidylinositol (GPI) transamidase (GPIT), the enzyme that attaches GPI anchors to proteins as they enter the lumen of the endoplasmic reticulum, is a membrane-bound hetero-pentameric complex consisting of Gpi8, Gpi16, Gaa1, Gpi17 and Gab1. Here, we expressed and purified the luminal do...

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Detalles Bibliográficos
Autores principales: Yi, Lina, Bozkurt, Gunes, Li, Qiubai, Lo, Stanley, Menon, Anant K., Wu, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379210/
https://www.ncbi.nlm.nih.gov/pubmed/28374821
http://dx.doi.org/10.1038/srep45912

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379210/
https://www.ncbi.nlm.nih.gov/pubmed/28374821
http://dx.doi.org/10.1038/srep45912

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