Cargando…

Inhibitory Effects of Dopamine Receptor D(1) Agonist on Mammary Tumor and Bone Metastasis

Dopaminergic signaling plays a critical role in the nervous system, but little is known about its potential role in breast cancer and bone metabolism. A screening of ~1,000 biologically active compounds revealed that a selective agonist of dopamine receptor D1 (DRD1), A77636, inhibited proliferation...

Descripción completa

Detalles Bibliográficos
Autores principales: Minami, Kazumasa, Liu, Shengzhi, Liu, Yang, Chen, Andy, Wan, Qiaoqiao, Na, Sungsoo, Li, Bai-Yan, Matsuura, Nariaki, Koizumi, Masahiko, Yin, Yukun, Gan, Liangying, Xu, Aihua, Li, Jiliang, Nakshatri, Harikrishna, Yokota, Hiroki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379485/
https://www.ncbi.nlm.nih.gov/pubmed/28374823
http://dx.doi.org/10.1038/srep45686