Antiviral efficacy of entecavir for hepatitis B virus rtA181V/T mutants

BACKGROUND: The amino acid substitution at position 181 of the Hepatitis B virus (HBV) polymerase is a multi-drug resistance affecting both the L-nucleoside and acyclic phosphonate nucleotide groups. Data is limited on the efficacy of entecavir (ETV) rescuing chronic hepatitis B (CHB) patients with...

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Detalles Bibliográficos
Autores principales: Li, Ping, Geng, Jiabao, Li, Wei, Xu, Xiaobing, Zhang, Xin, Zheng, Wenkai, Yu, Yuecheng, Yang, Zhiguo, Wang, Maorong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379510/
https://www.ncbi.nlm.nih.gov/pubmed/28376852
http://dx.doi.org/10.1186/s12985-017-0739-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379510/
https://www.ncbi.nlm.nih.gov/pubmed/28376852
http://dx.doi.org/10.1186/s12985-017-0739-z

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