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Multiple gene variations contributed to congenital heart disease via GATA family transcriptional regulation

BACKGROUND: Congenital heart disease (CHD) is a common birth defect, and most cases occur sporadically. Mutations in key genes that are responsible for cardiac development could contribute to CHD. To date, the genetic causes of CHD remain largely unknown. METHODS: In this study, twenty-nine candidat...

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Detalles Bibliográficos
Autores principales: Qian, Yanyan, Xiao, Deyong, Guo, Xiao, Chen, Hongbo, Hao, Lili, Ma, Xiaojing, Huang, Guoying, Ma, Duan, Wang, Huijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379520/
https://www.ncbi.nlm.nih.gov/pubmed/28372585
http://dx.doi.org/10.1186/s12967-017-1173-0