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Let-7e sensitizes epithelial ovarian cancer to cisplatin through repressing DNA double strand break repair
BACKGROUND: Resistance to platinum-based chemotherapy remains a great challenge for ovarian cancer treatment. The human let-7 family contains 13 members located on nine different chromosomes, and most members have been implicated in the modulation of drug sensitivity in cancers. Our previous study s...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379542/ https://www.ncbi.nlm.nih.gov/pubmed/28376831 http://dx.doi.org/10.1186/s13048-017-0321-8 |