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Transcription factors regulate GPR91-mediated expression of VEGF in hypoxia-induced retinopathy

Hypoxia is the most important factor in the pathogenesis of diabetic retinopathy (DR). Our previous studies demonstrated that G protein-coupled receptor 91(GPR91) participated in the regulation of vascular endothelial growth factor (VEGF) secretion in DR. The present study induced OIR model in newbo...

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Detalles Bibliográficos
Autores principales: Li, Tingting, Hu, Jianyan, Gao, Fengjuan, Du, Xinhua, Chen, Yongdong, Wu, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379554/
https://www.ncbi.nlm.nih.gov/pubmed/28374767
http://dx.doi.org/10.1038/srep45807