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Human induced-pluripotent stem cell-derived hepatocyte-like cells as an in vitro model of human hepatitis B virus infection

In order to understand the life cycle of hepatitis B virus (HBV) and to develop efficient anti-HBV drugs, a useful in vitro cell culture system which allows HBV infection and recapitulates virus-host interactions is essential; however, pre-existing in vitro HBV infection models are often problematic...

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Detalles Bibliográficos
Autores principales: Sakurai, Fuminori, Mitani, Seiji, Yamamoto, Tatsuro, Takayama, Kazuo, Tachibana, Masashi, Watashi, Koichi, Wakita, Takaji, Iijima, Sayuki, Tanaka, Yasuhito, Mizuguchi, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379564/
https://www.ncbi.nlm.nih.gov/pubmed/28374759
http://dx.doi.org/10.1038/srep45698