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The depletion of PinX1 involved in the tumorigenesis of non-small cell lung cancer promotes cell proliferation via p15/cyclin D1 pathway

BACKGROUND: The telomerase/telomere interacting protein PinX1 has been suggested as a tumor suppressor. However, the clinical and biological significance of PinX1 in human non-small cell lung cancer (NSCLC) is unclear. METHODS: PinX1 gene/expression pattern and its association with NSCLC patient sur...

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Detalles Bibliográficos
Autores principales: Tian, Xiao-Peng, Jin, Xiao-Han, Li, Mei, Huang, Wei-Juan, Xie, Dan, Zhang, Jia-Xing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379637/
https://www.ncbi.nlm.nih.gov/pubmed/28372542
http://dx.doi.org/10.1186/s12943-017-0637-4