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The depletion of PinX1 involved in the tumorigenesis of non-small cell lung cancer promotes cell proliferation via p15/cyclin D1 pathway
BACKGROUND: The telomerase/telomere interacting protein PinX1 has been suggested as a tumor suppressor. However, the clinical and biological significance of PinX1 in human non-small cell lung cancer (NSCLC) is unclear. METHODS: PinX1 gene/expression pattern and its association with NSCLC patient sur...
Autores principales: | Tian, Xiao-Peng, Jin, Xiao-Han, Li, Mei, Huang, Wei-Juan, Xie, Dan, Zhang, Jia-Xing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379637/ https://www.ncbi.nlm.nih.gov/pubmed/28372542 http://dx.doi.org/10.1186/s12943-017-0637-4 |
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