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Evaluation of the immunogenicity and safety of different doses and formulations of a broad spectrum influenza vaccine (FLU-v) developed by SEEK: study protocol for a single-center, randomized, double-blind and placebo-controlled clinical phase IIb trial

BACKGROUND: Current influenza vaccines, based on antibodies against surface antigens, are unable to provide protection against newly emerging virus strains which differ from the vaccine strains. Therefore the population has to be re-vaccinated annually. It is thus important to develop vaccines which...

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Detalles Bibliográficos
Autores principales: van Doorn, Eva, Pleguezuelos, Olga, Liu, Heng, Fernandez, Ana, Bannister, Robin, Stoloff, Gregory, Oftung, Fredrik, Norley, Stephen, Huckriede, Anke, Frijlink, Henderik W., Hak, Eelko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379643/
https://www.ncbi.nlm.nih.gov/pubmed/28376743
http://dx.doi.org/10.1186/s12879-017-2341-9