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Coordinating antigen cytosolic delivery and danger signaling to program potent cross-priming by micelle-based nanovaccine
Although re-activating cytotoxic T-cell (CTLs) response inside tumor tissues by checkpoint blockade has demonstrated great success in tumor immunotherapy, active induction of efficient endogenous CTL response by therapeutic vaccines has been largely hampered by inefficient cytosolic delivery of anti...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379745/ https://www.ncbi.nlm.nih.gov/pubmed/28417012 http://dx.doi.org/10.1038/celldisc.2017.7 |