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Coordinating antigen cytosolic delivery and danger signaling to program potent cross-priming by micelle-based nanovaccine

Although re-activating cytotoxic T-cell (CTLs) response inside tumor tissues by checkpoint blockade has demonstrated great success in tumor immunotherapy, active induction of efficient endogenous CTL response by therapeutic vaccines has been largely hampered by inefficient cytosolic delivery of anti...

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Detalles Bibliográficos
Autores principales: Liu, Zhida, Zhou, Chang, Qin, Yan, Wang, Zihao, Wang, Luyao, Wei, Xiuli, Zhou, Yinjian, Li, Qicheng, Zhou, Hang, Wang, Wenjun, Fu, Yang-Xin, Zhu, Mingzhao, Liang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379745/
https://www.ncbi.nlm.nih.gov/pubmed/28417012
http://dx.doi.org/10.1038/celldisc.2017.7