TGFBR2-dependent alterations of exosomal cargo and functions in DNA mismatch repair-deficient HCT116 colorectal cancer cells

BACKGROUND: Colorectal cancers (CRCs) that lack DNA mismatch repair function exhibit the microsatellite unstable (MSI) phenotype and are characterized by the accumulation of frameshift mutations at short repetitive DNA sequences (microsatellites). These tumors recurrently show inactivating frameshif...

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Detalles Bibliográficos
Autores principales: Fricke, Fabia, Lee, Jennifer, Michalak, Malwina, Warnken, Uwe, Hausser, Ingrid, Suarez-Carmona, Meggy, Halama, Niels, Schnölzer, Martina, Kopitz, Jürgen, Gebert, Johannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379773/
https://www.ncbi.nlm.nih.gov/pubmed/28376875
http://dx.doi.org/10.1186/s12964-017-0169-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379773/
https://www.ncbi.nlm.nih.gov/pubmed/28376875
http://dx.doi.org/10.1186/s12964-017-0169-y

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