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The chemokine CXCL12 mediates the anti-amyloidogenic action of painless human nerve growth factor

Nerve growth factor is a therapeutic candidate for Alzheimer’s disease. Due to its pain-inducing activity, in current clinical trials nerve growth factor is delivered locally into the brain by neurosurgery, but data on the efficacy of local nerve growth factor delivery in decreasing amyloid-β deposi...

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Detalles Bibliográficos
Autores principales: Capsoni, Simona, Malerba, Francesca, Carucci, Nicola Maria, Rizzi, Caterina, Criscuolo, Chiara, Origlia, Nicola, Calvello, Mariantonietta, Viegi, Alessandro, Meli, Giovanni, Cattaneo, Antonino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379860/
https://www.ncbi.nlm.nih.gov/pubmed/28031222
http://dx.doi.org/10.1093/brain/aww271