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Evolutionary insights into T-type Ca(2+) channel structure, function, and ion selectivity from the Trichoplax adhaerens homologue
Four-domain voltage-gated Ca(2+) (Ca(v)) channels play fundamental roles in the nervous system, but little is known about when or how their unique properties and cellular roles evolved. Of the three types of metazoan Ca(v) channels, Ca(v)1 (L-type), Ca(v)2 (P/Q-, N- and R-type) and Ca(v)3 (T-type),...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379919/ https://www.ncbi.nlm.nih.gov/pubmed/28330839 http://dx.doi.org/10.1085/jgp.201611683 |