Evolutionary insights into T-type Ca(2+) channel structure, function, and ion selectivity from the Trichoplax adhaerens homologue

Four-domain voltage-gated Ca(2+) (Ca(v)) channels play fundamental roles in the nervous system, but little is known about when or how their unique properties and cellular roles evolved. Of the three types of metazoan Ca(v) channels, Ca(v)1 (L-type), Ca(v)2 (P/Q-, N- and R-type) and Ca(v)3 (T-type),...

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Detalles Bibliográficos
Autores principales: Smith, Carolyn L., Abdallah, Salsabil, Wong, Yuen Yan, Le, Phuong, Harracksingh, Alicia N., Artinian, Liana, Tamvacakis, Arianna N., Rehder, Vincent, Reese, Thomas S., Senatore, Adriano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379919/
https://www.ncbi.nlm.nih.gov/pubmed/28330839
http://dx.doi.org/10.1085/jgp.201611683

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