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Mechanism of single- and double-sided inhibition of dual topology fluoride channels by synthetic monobodies
The Fluc family of proteins comprises small, electrodiffusive fluoride channels, which prevent accumulation of toxic F(−) ions in microorganisms. Recent crystal structures have confirmed their unusual architecture, in which a pair of antiparallel subunits convenes to form a dimer with a twofold symm...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379923/ https://www.ncbi.nlm.nih.gov/pubmed/28258203 http://dx.doi.org/10.1085/jgp.201611747 |