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Mechanism of single- and double-sided inhibition of dual topology fluoride channels by synthetic monobodies

The Fluc family of proteins comprises small, electrodiffusive fluoride channels, which prevent accumulation of toxic F(−) ions in microorganisms. Recent crystal structures have confirmed their unusual architecture, in which a pair of antiparallel subunits convenes to form a dimer with a twofold symm...

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Detalles Bibliográficos
Autores principales: Turman, Daniel L., Stockbridge, Randy B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379923/
https://www.ncbi.nlm.nih.gov/pubmed/28258203
http://dx.doi.org/10.1085/jgp.201611747