Unique spectral signatures of the nucleic acid dye acridine orange can distinguish cell death by apoptosis and necroptosis

Cellular injury and death are ubiquitous features of disease, yet tools to detect them are limited and insensitive to subtle pathological changes. Acridine orange (AO), a nucleic acid dye with unique spectral properties, enables real-time measurement of RNA and DNA as proxies for cell viability duri...

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Detalles Bibliográficos
Autores principales: Plemel, Jason R., Caprariello, Andrew V., Keough, Michael B., Henry, Tyler J., Tsutsui, Shigeki, Chu, Tak H., Schenk, Geert J., Klaver, Roel, Yong, V. Wee, Stys, Peter K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379938/
https://www.ncbi.nlm.nih.gov/pubmed/28264914
http://dx.doi.org/10.1083/jcb.201602028

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379938/
https://www.ncbi.nlm.nih.gov/pubmed/28264914
http://dx.doi.org/10.1083/jcb.201602028

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