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ELKS1 localizes the synaptic vesicle priming protein bMunc13-2 to a specific subset of active zones

Presynaptic active zones (AZs) are unique subcellular structures at neuronal synapses, which contain a network of specific proteins that control synaptic vesicle (SV) tethering, priming, and fusion. Munc13s are core AZ proteins with an essential function in SV priming. In hippocampal neurons, two di...

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Detalles Bibliográficos
Autores principales: Kawabe, Hiroshi, Mitkovski, Miso, Kaeser, Pascal S., Hirrlinger, Johannes, Opazo, Felipe, Nestvogel, Dennis, Kalla, Stefan, Fejtova, Anna, Verrier, Sophie E., Bungers, Simon R., Cooper, Benjamin H., Varoqueaux, Frederique, Wang, Yun, Nehring, Ralf B., Gundelfinger, Eckart D., Rosenmund, Christian, Rizzoli, Silvio O., Südhof, Thomas C., Rhee, Jeong-Seop, Brose, Nils
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379939/
https://www.ncbi.nlm.nih.gov/pubmed/28264913
http://dx.doi.org/10.1083/jcb.201606086