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ELKS1 localizes the synaptic vesicle priming protein bMunc13-2 to a specific subset of active zones
Presynaptic active zones (AZs) are unique subcellular structures at neuronal synapses, which contain a network of specific proteins that control synaptic vesicle (SV) tethering, priming, and fusion. Munc13s are core AZ proteins with an essential function in SV priming. In hippocampal neurons, two di...
Autores principales: | Kawabe, Hiroshi, Mitkovski, Miso, Kaeser, Pascal S., Hirrlinger, Johannes, Opazo, Felipe, Nestvogel, Dennis, Kalla, Stefan, Fejtova, Anna, Verrier, Sophie E., Bungers, Simon R., Cooper, Benjamin H., Varoqueaux, Frederique, Wang, Yun, Nehring, Ralf B., Gundelfinger, Eckart D., Rosenmund, Christian, Rizzoli, Silvio O., Südhof, Thomas C., Rhee, Jeong-Seop, Brose, Nils |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379939/ https://www.ncbi.nlm.nih.gov/pubmed/28264913 http://dx.doi.org/10.1083/jcb.201606086 |
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