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Telomere-driven diseases and telomere-targeting therapies

Telomeres, the protective ends of linear chromosomes, shorten throughout an individual’s lifetime. Telomere shortening is proposed to be a primary molecular cause of aging. Short telomeres block the proliferative capacity of stem cells, affecting their potential to regenerate tissues, and trigger th...

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Detalles Bibliográficos
Autores principales: Martínez, Paula, Blasco, Maria A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379954/
https://www.ncbi.nlm.nih.gov/pubmed/28254828
http://dx.doi.org/10.1083/jcb.201610111