VEGF165-induced vascular permeability requires NRP1 for ABL-mediated SRC family kinase activation

The vascular endothelial growth factor (VEGF) isoform VEGF165 stimulates vascular growth and hyperpermeability. Whereas blood vessel growth is essential to sustain organ health, chronic hyperpermeability causes damaging tissue edema. By combining in vivo and tissue culture models, we show here that...

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Detalles Bibliográficos
Autores principales: Fantin, Alessandro, Lampropoulou, Anastasia, Senatore, Valentina, Brash, James T., Prahst, Claudia, Lange, Clemens A., Liyanage, Sidath E., Raimondi, Claudio, Bainbridge, James W., Augustin, Hellmut G., Ruhrberg, Christiana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379968/
https://www.ncbi.nlm.nih.gov/pubmed/28289053
http://dx.doi.org/10.1084/jem.20160311

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379968/
https://www.ncbi.nlm.nih.gov/pubmed/28289053
http://dx.doi.org/10.1084/jem.20160311

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