Myeloid-derived cullin 3 promotes STAT3 phosphorylation by inhibiting OGT expression and protects against intestinal inflammation

Signal transducer and activator of transcription 3 (STAT3) is a key mediator of intestinal inflammation and tumorigenesis. However, the molecular mechanism that modulates STAT3 phosphorylation and activation is not fully understood. Here, we demonstrate that modification of STAT3 with O-linked β-N-a...

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Detalles Bibliográficos
Autores principales: Li, Xinghui, Zhang, Zhibin, Li, Lupeng, Gong, Wei, Lazenby, Audrey J., Swanson, Benjamin J., Herring, Laura E., Asara, John M., Singer, Jeffrey D., Wen, Haitao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379975/
https://www.ncbi.nlm.nih.gov/pubmed/28280036
http://dx.doi.org/10.1084/jem.20161105

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379975/
https://www.ncbi.nlm.nih.gov/pubmed/28280036
http://dx.doi.org/10.1084/jem.20161105

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