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ZMPSTE24 defends against influenza and other pathogenic viruses

Zinc metallopeptidase STE24 (ZMPSTE24) is a transmembrane metalloprotease whose catalytic activity is critical for processing lamin A on the inner nuclear membrane and clearing clogged translocons on the endoplasmic reticulum. We now report ZMPSTE24 is a virus-specific effector that restricts envelo...

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Detalles Bibliográficos
Autores principales: Fu, Bishi, Wang, Lingyan, Li, Shitao, Dorf, Martin E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379977/
https://www.ncbi.nlm.nih.gov/pubmed/28246125
http://dx.doi.org/10.1084/jem.20161270