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p38 inhibition provides anti–DNA virus immunity by regulation of USP21 phosphorylation and STING activation
Stimulator of IFN genes (STING) is a central adaptor protein that mediates the innate immune responses to DNA virus infection. Although ubiquitination is essential for STING function, how the ubiquitination/deubiquitination system is regulated by virus infection to control STING activity remains unk...
Autores principales: | , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379979/ https://www.ncbi.nlm.nih.gov/pubmed/28254948 http://dx.doi.org/10.1084/jem.20161387 |