p38 inhibition provides anti–DNA virus immunity by regulation of USP21 phosphorylation and STING activation

Stimulator of IFN genes (STING) is a central adaptor protein that mediates the innate immune responses to DNA virus infection. Although ubiquitination is essential for STING function, how the ubiquitination/deubiquitination system is regulated by virus infection to control STING activity remains unk...

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Detalles Bibliográficos
Autores principales: Chen, Yunfei, Wang, Lufan, Jin, Jiali, Luan, Yi, Chen, Cong, Li, Yu, Chu, Hongshang, Wang, Xinbo, Liao, Guanghong, Yu, Yue, Teng, Hongqi, Wang, Yanming, Pan, Weijuan, Fang, Lan, Liao, Lujian, Jiang, Zhengfan, Ge, Xin, Li, Bin, Wang, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379979/
https://www.ncbi.nlm.nih.gov/pubmed/28254948
http://dx.doi.org/10.1084/jem.20161387

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