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Metallothionein, Copper and Alpha-Synuclein in Alpha-Synucleinopathies

Metallothioneins (MTs) are proteins that function by metal exchange to regulate the bioavailability of metals, such as zinc and copper. Copper functions in the brain to regulate mitochondria, neurotransmitter production, and cell signaling. Inappropriate copper binding can result in loss of protein...

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Detalles Bibliográficos
Autores principales: Okita, Yuho, Rcom-H'cheo-Gauthier, Alexandre N., Goulding, Michael, Chung, Roger S., Faller, Peter, Pountney, Dean L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5380005/
https://www.ncbi.nlm.nih.gov/pubmed/28420950
http://dx.doi.org/10.3389/fnins.2017.00114