Clustered Distribution of Natural Product Leads of Drugs in the Chemical Space as Influenced by the Privileged Target-Sites

Some natural product leads of drugs (NPLDs) have been found to congregate in the chemical space. The extent, detailed patterns, and mechanisms of this congregation phenomenon have not been fully investigated and their usefulness for NPLD discovery needs to be more extensively tested. In this work, w...

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Detalles Bibliográficos
Autores principales: Tao, Lin, Zhu, Feng, Qin, Chu, Zhang, Cheng, Chen, Shangying, Zhang, Peng, Zhang, Cunlong, Tan, Chunyan, Gao, Chunmei, Chen, Zhe, Jiang, Yuyang, Chen, Yu Zong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5380136/
https://www.ncbi.nlm.nih.gov/pubmed/25790752
http://dx.doi.org/10.1038/srep09325

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5380136/
https://www.ncbi.nlm.nih.gov/pubmed/25790752
http://dx.doi.org/10.1038/srep09325

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