RPL5 on 1p22.1 is recurrently deleted in multiple myeloma and its expression is linked to bortezomib response

Chromosomal region 1p22 is deleted in ≥20% of multiple myeloma (MM) patients, suggesting the presence of an unidentified tumor suppressor. Using high-resolution genomic profiling, we delimit a 58 kb minimal deleted region (MDR) on 1p22.1 encompassing two genes: ectopic viral integration site 5 (EVI5...

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Detalles Bibliográficos
Autores principales: Hofman, Isabel JF, Van Duin, Mark, De Bruyne, Elke, Fancello, Laura, Mulligan, George, Geerdens, Ellen, Garelli, Emanuela, Mancini, Cecilia, Lemmens, Heidi, Delforge, Michel, Vandenberghe, Peter, Wlodarska, Iwona, Aspesi, Anna, Michaux, Lucienne, Vanderkerken, Karin, Sonneveld, Pieter, De Keersmaecker, Kim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5380219/
https://www.ncbi.nlm.nih.gov/pubmed/27909306
http://dx.doi.org/10.1038/leu.2016.370

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5380219/
https://www.ncbi.nlm.nih.gov/pubmed/27909306
http://dx.doi.org/10.1038/leu.2016.370

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