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Elucidation of the calcineurin-Crz1 stress response transcriptional network in the human fungal pathogen Cryptococcus neoformans

Calcineurin is a highly conserved Ca(2+)/calmodulin-dependent serine/threonine-specific protein phosphatase that orchestrates cellular Ca(2+) signaling responses. In Cryptococcus neoformans, calcineurin is activated by multiple stresses including high temperature, and is essential for stress adaptat...

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Detalles Bibliográficos
Autores principales: Chow, Eve W. L., Clancey, Shelly A., Billmyre, R. Blake, Averette, Anna Floyd, Granek, Joshua A., Mieczkowski, Piotr, Cardenas, Maria E., Heitman, Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5380312/
https://www.ncbi.nlm.nih.gov/pubmed/28376087
http://dx.doi.org/10.1371/journal.pgen.1006667