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Quantifying Adhesion Mechanisms and Dynamics of Human Hematopoietic Stem and Progenitor Cells
Using planar lipid membranes with precisely defined concentrations of specific ligands, we have determined the binding strength between human hematopoietic stem cells (HSC) and the bone marrow niche. The relative significance of HSC adhesion to the surrogate niche models via SDF1α-CXCR4 or N-cadheri...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5380331/ https://www.ncbi.nlm.nih.gov/pubmed/25824493 http://dx.doi.org/10.1038/srep09370 |