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Quantifying Adhesion Mechanisms and Dynamics of Human Hematopoietic Stem and Progenitor Cells

Using planar lipid membranes with precisely defined concentrations of specific ligands, we have determined the binding strength between human hematopoietic stem cells (HSC) and the bone marrow niche. The relative significance of HSC adhesion to the surrogate niche models via SDF1α-CXCR4 or N-cadheri...

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Detalles Bibliográficos
Autores principales:	Burk, Alexandra S., Monzel, Cornelia, Yoshikawa, Hiroshi Y., Wuchter, Patrick, Saffrich, Rainer, Eckstein, Volker, Tanaka, Motomu, Ho, Anthony D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5380331/ https://www.ncbi.nlm.nih.gov/pubmed/25824493 http://dx.doi.org/10.1038/srep09370

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