Genome-wide RNAi selection identifies a regulator of transmission stage-enriched gene families and cell-type differentiation in Trypanosoma brucei

Trypanosoma brucei, causing African sleeping-sickness, exploits quorum-sensing (QS) to generate the ‘stumpy forms’ necessary for the parasite’s transmission to tsetse-flies. These quiescent cells are generated by differentiation in the bloodstream from proliferative slender forms. Using genome-wide...

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Detalles Bibliográficos
Autores principales: Rico, Eva, Ivens, Alasdair, Glover, Lucy, Horn, David, Matthews, Keith R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5380359/
https://www.ncbi.nlm.nih.gov/pubmed/28334017
http://dx.doi.org/10.1371/journal.ppat.1006279

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5380359/
https://www.ncbi.nlm.nih.gov/pubmed/28334017
http://dx.doi.org/10.1371/journal.ppat.1006279

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