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Assessment of Toxicological Perturbations and Variants of Pancreatic Islet Development in the Zebrafish Model

The pancreatic islets, largely comprised of insulin-producing beta cells, play a critical role in endocrine signaling and glucose homeostasis. Because they have low levels of antioxidant defenses and a high perfusion rate, the endocrine islets may be a highly susceptible target tissue of chemical ex...

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Detalles Bibliográficos
Autores principales: Sant, Karilyn E., Jacobs, Haydee M., Xu, Jiali, Borofski, Katrina A., Moss, Larry G., Moss, Jennifer B., Timme-Laragy, Alicia R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5380372/
https://www.ncbi.nlm.nih.gov/pubmed/28393070
http://dx.doi.org/10.3390/toxics4030020