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Assessment of Toxicological Perturbations and Variants of Pancreatic Islet Development in the Zebrafish Model
The pancreatic islets, largely comprised of insulin-producing beta cells, play a critical role in endocrine signaling and glucose homeostasis. Because they have low levels of antioxidant defenses and a high perfusion rate, the endocrine islets may be a highly susceptible target tissue of chemical ex...
Autores principales: | Sant, Karilyn E., Jacobs, Haydee M., Xu, Jiali, Borofski, Katrina A., Moss, Larry G., Moss, Jennifer B., Timme-Laragy, Alicia R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5380372/ https://www.ncbi.nlm.nih.gov/pubmed/28393070 http://dx.doi.org/10.3390/toxics4030020 |
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