Unique charge-dependent constraint on collagen recognition by integrin α10β1

The collagen-binding integrins recognise collagen through their inserted (I) domain, where co-ordination of a Mg(2 +) ion in the metal ion-dependent site is reorganised by ligation by a collagen glutamate residue found in specific collagen hexapeptide motifs. Here we show that GROGER, found in the N...

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Detalles Bibliográficos
Autores principales: Hamaia, Samir W., Luff, Daisy, Hunter, Emma J., Malcor, Jean-Daniel, Bihan, Dominique, Gullberg, Donald, Farndale, Richard W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5380659/
https://www.ncbi.nlm.nih.gov/pubmed/27569273
http://dx.doi.org/10.1016/j.matbio.2016.08.010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5380659/
https://www.ncbi.nlm.nih.gov/pubmed/27569273
http://dx.doi.org/10.1016/j.matbio.2016.08.010

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