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Unique charge-dependent constraint on collagen recognition by integrin α10β1
The collagen-binding integrins recognise collagen through their inserted (I) domain, where co-ordination of a Mg(2 +) ion in the metal ion-dependent site is reorganised by ligation by a collagen glutamate residue found in specific collagen hexapeptide motifs. Here we show that GROGER, found in the N...
Autores principales: | Hamaia, Samir W., Luff, Daisy, Hunter, Emma J., Malcor, Jean-Daniel, Bihan, Dominique, Gullberg, Donald, Farndale, Richard W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5380659/ https://www.ncbi.nlm.nih.gov/pubmed/27569273 http://dx.doi.org/10.1016/j.matbio.2016.08.010 |
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