A novel scalable, robust downstream process for oncolytic rat parvovirus: isoelectric point-based elimination of empty particles

The rodent protoparvovirus H-1PV, with its oncolytic and oncosuppressive properties, is a promising anticancer agent currently under testing in clinical trials. This explains the current demand for a scalable, good manufacturing practice-compatible virus purification process yielding high-grade pure...

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Detalles Bibliográficos
Autores principales: Leuchs, Barbara, Frehtman, Veronika, Riese, Markus, Müller, Marcus, Rommelaere, Jean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Biotechnological Products and Process Engineering
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5380694/
https://www.ncbi.nlm.nih.gov/pubmed/28091791
http://dx.doi.org/10.1007/s00253-016-8071-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5380694/
https://www.ncbi.nlm.nih.gov/pubmed/28091791
http://dx.doi.org/10.1007/s00253-016-8071-x

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