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Relationship between Cognitive and Sleep–wake Variables in Asymptomatic Offspring of Patients with Late-onset Alzheimer’s Disease

Early neuropathological changes characteristic of late-onset Alzheimer’s disease (LOAD) involve brain stem and limbic structures that regulate neurovegetative functions, including sleep–wake rhythm. Indeed, sleep pattern is an emerging biomarker and a potential pathophysiological mechanism in LOAD....

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Detalles Bibliográficos
Autores principales: Abulafia, Carolina, Duarte-Abritta, Bárbara, Villarreal, Mirta F., Ladrón-de-Guevara, María S., García, Celeste, Sequeyra, Geraldine, Sevlever, Gustavo, Fiorentini, Leticia, Bär, Karl-Jürgen, Gustafson, Deborah R., Vigo, Daniel E., Guinjoan, Salvador M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5380732/
https://www.ncbi.nlm.nih.gov/pubmed/28424614
http://dx.doi.org/10.3389/fnagi.2017.00093