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Relationship between Cognitive and Sleep–wake Variables in Asymptomatic Offspring of Patients with Late-onset Alzheimer’s Disease
Early neuropathological changes characteristic of late-onset Alzheimer’s disease (LOAD) involve brain stem and limbic structures that regulate neurovegetative functions, including sleep–wake rhythm. Indeed, sleep pattern is an emerging biomarker and a potential pathophysiological mechanism in LOAD....
Autores principales: | Abulafia, Carolina, Duarte-Abritta, Bárbara, Villarreal, Mirta F., Ladrón-de-Guevara, María S., García, Celeste, Sequeyra, Geraldine, Sevlever, Gustavo, Fiorentini, Leticia, Bär, Karl-Jürgen, Gustafson, Deborah R., Vigo, Daniel E., Guinjoan, Salvador M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5380732/ https://www.ncbi.nlm.nih.gov/pubmed/28424614 http://dx.doi.org/10.3389/fnagi.2017.00093 |
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