Valproic Acid Protects Primary Dopamine Neurons from MPP(+)-Induced Neurotoxicity: Involvement of GSK3β Phosphorylation by Akt and ERK through the Mitochondrial Intrinsic Apoptotic Pathway

Valproic acid (VPA), a drug widely used to treat manic disorder and epilepsy, has recently shown neuroprotective effects in several neurological diseases, particularly in Parkinson's disease (PD). The goal of the present study was to confirm VPA's dose-dependent neuroprotective propensitie...

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Detalles Bibliográficos
Autores principales: Zhang, Chi, Yuan, Xianrui, Hu, Zhongliang, Liu, Songlin, Li, Haoyu, Wu, Ming, Yuan, Jian, Zhao, Zijin, Su, Jun, Wang, Xiangyu, Liao, Yiwei, Liu, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5380829/
https://www.ncbi.nlm.nih.gov/pubmed/28421199
http://dx.doi.org/10.1155/2017/8124501

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5380829/
https://www.ncbi.nlm.nih.gov/pubmed/28421199
http://dx.doi.org/10.1155/2017/8124501

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