The R263K Dolutegravir Resistance-Associated Substitution Progressively Decreases HIV-1 Integration

Human immunodeficiency virus (HIV) infection persists despite decades of active antiretroviral therapy (ART), effectively preventing viral eradication. Treatment decreases plasma viral RNA, but viral DNA persists, mostly integrated within the genome of nucleated blood cells. Viral DNA blood levels c...

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Detalles Bibliográficos
Autores principales: Mesplède, Thibault, Leng, Jing, Pham, Hanh Thi, Liang, Jiaming, Quan, Yudong, Han, Yingshan, Wainberg, Mark A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5380839/
https://www.ncbi.nlm.nih.gov/pubmed/28377526
http://dx.doi.org/10.1128/mBio.00157-17

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5380839/
https://www.ncbi.nlm.nih.gov/pubmed/28377526
http://dx.doi.org/10.1128/mBio.00157-17

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