Excess of Aminopeptidase A in the Brain Elevates Blood Pressure via the Angiotensin II Type 1 and Bradykinin B2 Receptors without Dipsogenic Effect

Aminopeptidase A (APA) cleaves angiotensin (Ang) II, kallidin, and other related peptides. In the brain, it activates the renin angiotensin system and causes hypertension. Limited data are available on the dipsogenic effect of APA and pressor effect of degraded peptides of APA such as bradykinin. Wi...

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Detalles Bibliográficos
Autores principales: Nakamura, Takuto, Yamazato, Masanobu, Ishida, Akio, Ohya, Yusuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5380851/
https://www.ncbi.nlm.nih.gov/pubmed/28421141
http://dx.doi.org/10.1155/2017/3967595

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5380851/
https://www.ncbi.nlm.nih.gov/pubmed/28421141
http://dx.doi.org/10.1155/2017/3967595

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