Cargando…

Excess of Aminopeptidase A in the Brain Elevates Blood Pressure via the Angiotensin II Type 1 and Bradykinin B2 Receptors without Dipsogenic Effect

Aminopeptidase A (APA) cleaves angiotensin (Ang) II, kallidin, and other related peptides. In the brain, it activates the renin angiotensin system and causes hypertension. Limited data are available on the dipsogenic effect of APA and pressor effect of degraded peptides of APA such as bradykinin. Wi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nakamura, Takuto, Yamazato, Masanobu, Ishida, Akio, Ohya, Yusuke
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5380851/ https://www.ncbi.nlm.nih.gov/pubmed/28421141 http://dx.doi.org/10.1155/2017/3967595

Ejemplares similares

Elevated Aminopeptidase P Attenuates Cerebral Arterial Responses to Bradykinin in Fawn-Hooded Hypertensive Rats
por: Khan, Md Abdul Hye, et al.
Publicado: (2015)

Power spectral analysis of heart rate variability is useful as a screening tool for detecting sympathetic and parasympathetic nervous dysfunctions in Parkinson’s disease
por: Miyagi, Tomo, et al.
Publicado: (2022)

Acquired factor V inhibitor with erythema and eosinophilia in a patient with end-stage renal disease
por: Katsuren, Eisuke, et al.
Publicado: (2022)

Add-On Effect of Angiotensin Receptor Blockade (Candesartan) on Clinical Remission in Active IgA Nephropathy Patients Treated with Steroid Pulse Therapy and Tonsillectomy: a Randomized, Parallel-Group Comparison Trial
por: Kohagura, Kentaro, et al.
Publicado: (2018)

Suppression of TRPV4 channels ameliorates anti-dipsogenic effects under hypoxia in the subfornical organ of rats
por: Yang, Fan, et al.
Publicado: (2016)

The anti‐dipsogenic and anti‐natriorexigenic effects of estradiol, but not the anti‐pressor effect, are lost in aged female rats
por: Santollo, Jessica, et al.
Publicado: (2021)

Vasomotor effects of 5-hydroxytryptamine, histamine, angiotensin II, acetylcholine, noradrenaline, and bradykinin on the cerebral artery of bottlenose dolphin (Tursiops truncatus)
por: ISLAM, Md. Zahorul, et al.
Publicado: (2020)

Over diagnosis of bradykinin angioedema in patients treated with angiotensin-converting enzyme inhibitors or angiotensin II receptor blockers()
por: Douillard, Marie, et al.
Publicado: (2023)

The Association of Smoking and Hyperuricemia with Renal Arteriolosclerosis in IgA Nephropathy
por: Shinzato, Yuki, et al.
Publicado: (2023)

Focus on Brain Angiotensin III and Aminopeptidase A in the Control of Hypertension
por: Wright, John W., et al.
Publicado: (2012)

THU596 Heteromerization Of The Angiotensin II Type 1 Receptor And The Bradykinin Type 2 Receptor
por: Johnstone, Elizabeth K M, et al.
Publicado: (2023)

From Angiotensin IV to Small Peptidemimetics Inhibiting Insulin-Regulated Aminopeptidase
por: Hallberg, Mathias, et al.
Publicado: (2020)

Vasomotor Effects of Acetylcholine, Bradykinin, Noradrenaline, 5-Hydroxytryptamine, Histamine and Angiotensin II on the Mouse Basilar Artery
por: ISLAM, Md. Zahorul, et al.
Publicado: (2014)

Novel Pharmacology Following Heteromerization of the Angiotensin II Type 2 Receptor and the Bradykinin Type 2 Receptor
por: Johnstone, Elizabeth K. M., et al.
Publicado: (2022)

ASSOCIATION BETWEEN BLOOD PRESSURE AND COGNITIVE FUNCTION OF COMMUNITY-DWELLING OLDEST OLD IN OKINAWA, JAPAN
por: Namihira, Yukihiro, et al.
Publicado: (2019)

Adropin Is a Key Mediator of Hypoxia Induced Anti-Dipsogenic Effects via TRPV4-CamKK-AMPK Signaling in the Circumventricular Organs of Rats
por: Yang, Fan, et al.
Publicado: (2017)

SAT-057 Endoplasmic Reticulum Aminopeptidase-1 Is a Novel Regulator of the Renin-Angiotensin-Aldosterone System and Blood Pressure Homeostasis
por: Ranjit, Sanjay
Publicado: (2019)

Combination of β Adrenergic Receptor Block and Renin–Angiotensin System Inhibition Diminished the Angiotensin II-Induced Vasoconstriction and Increased Bradykinin-Induced Vasodilation in Hypertension
por: Lezama-Martínez, Diego, et al.
Publicado: (2017)

Involvement of bradykinin and bradykinin B1 receptor in patients with endometriosis
por: Meng, Xin, et al.
Publicado: (2021)

Aminopeptidases
por: Sanz, Yolanda
Publicado: (2007)

The effect of insulin and enalapril on the potentiation of bradykinin-induced vasodilation by angiotensin-(1–7) in diabetes mellitus
por: Oliveira, MA, et al.
Publicado: (2003)

Administration of angiotensin II and a bradykinin B2 receptor blocker in midpregnancy impairs gestational outcome in guinea pigs
por: Valdés, Gloria, et al.
Publicado: (2014)

Phosphonic Acid Analogues of Phenylglycine as Inhibitors of Aminopeptidases: Comparison of Porcine Aminopeptidase N, Bovine Leucine Aminopeptidase, Tomato Acidic Leucine Aminopeptidase and Aminopeptidase from Barley Seeds
por: Wanat, Weronika, et al.
Publicado: (2019)

Bradykinin receptor expression and bradykinin-mediated sensitization of human sensory neurons
por: Yi, Jiwon, et al.
Publicado: (2023)

Reciprocal Expression Patterns of Placental Leucine Aminopeptidase/Insulin-Regulated Aminopeptidase and Vasopressin in the Murine Brain
por: Goto, Yoshikuni, et al.
Publicado: (2020)

Elevated aminopeptidase N affects sperm motility and early embryo development
por: Khatun, Amena, et al.
Publicado: (2017)

Neprilysin Inhibitors and Bradykinin
por: Campbell, Duncan J.
Publicado: (2018)

The bradykinin BK2 receptor mediates angiotensin II receptor type 2 stimulated rat duodenal mucosal alkaline secretion
por: Ewert, Sara, et al.
Publicado: (2003)

Effects of a Novel Bradykinin B1 Receptor Antagonist and Angiotensin II Receptor Blockade on Experimental Myocardial Infarction in Rats
por: Wu, Dongmei, et al.
Publicado: (2012)

Cardiovascular Risk Associated with Interactions among Polymorphisms in Genes from the Renin-Angiotensin, Bradykinin, and Fibrinolytic Systems
por: Bentley, John P., et al.
Publicado: (2010)

Potentiation of bradykinin actions by analogues of the bradykinin potentiating nonapeptide BPP(9α)
por: Mueller, Sylvia, et al.
Publicado: (2005)

Aminopeptidase N
por: Turner, Anthony J.
Publicado: (2013)

A Review of the Role of Bradykinin and Nitric Oxide in the Cardioprotective Action of Angiotensin-Converting Enzyme Inhibitors: Focus on Perindopril
por: Ancion, Arnaud, et al.
Publicado: (2019)

Combined angiotensin-converting enzyme and aminopeptidase inhibition for treatment of experimental ventilator-induced lung injury in mice
por: Mao, Xinjun, et al.
Publicado: (2023)

Bradykinin and the Pathogenesis of Hereditary Angioedema
por: Kaplan, Allen P
Publicado: (2011)

Cardiovascular Activities of of the bradykinin system
por: Sharma, Jagdish N.
Publicado: (2008)

Diabetic Nephropathy Induced by Increased Ace Gene Dosage Is Associated with High Renal Levels of Angiotensin (1–7) and Bradykinin
por: Bertoncello, Nádia, et al.
Publicado: (2015)

Interleukin 22 Promotes Blood Pressure Elevation and Endothelial Dysfunction in Angiotensin II–Treated Mice
por: Ye, Jing, et al.
Publicado: (2017)

Metallo-aminopeptidase inhibitors
por: Mucha, Artur, et al.
Publicado: (2010)

Membrane alanyl aminopeptidase
por: Turner, Anthony J.
Publicado: (2004)

Cannot write session to /tmp/vufind_sessions/sess_l62o7cb9j9hjpddn64nsuo5l8p