Activation of Sirtuin 3 by Silybin Attenuates Mitochondrial Dysfunction in Cisplatin-induced Acute Kidney Injury

Silybin is a secondary metabolite isolated from the seeds of blessed milk thistle (Silybum marianum) that has anti-inflammatory, antioxidative, antifibrotic, and antitumor properties. Here, we showed that silybin protected against cisplatin-induced acute kidney injury (AKI) by improving mitochondria...

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Detalles Bibliográficos
Autores principales: Li, Yin, Ye, Zengchun, Lai, Weiyan, Rao, Jialing, Huang, Wanbing, Zhang, Xiaohao, Yao, Ziying, Lou, Tanqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5380914/
https://www.ncbi.nlm.nih.gov/pubmed/28424621
http://dx.doi.org/10.3389/fphar.2017.00178

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5380914/
https://www.ncbi.nlm.nih.gov/pubmed/28424621
http://dx.doi.org/10.3389/fphar.2017.00178

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