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Immunoscreening of Plasmodium falciparum proteins expressed in a wheat germ cell-free system reveals a novel malaria vaccine candidate

The number of malaria vaccine candidates in preclinical and clinical development is limited. To identify novel blood-stage malaria vaccine candidates, we constructed a library of 1,827P. falciparum proteins prepared using the wheat germ cell-free system (WGCFS). Also, a high-throughput AlphaScreen p...

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Detalles Bibliográficos
Autores principales: Morita, Masayuki, Takashima, Eizo, Ito, Daisuke, Miura, Kazutoyo, Thongkukiatkul, Amporn, Diouf, Ababacar, Fairhurst, Rick M., Diakite, Mahamadou, Long, Carole A., Torii, Motomi, Tsuboi, Takafumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5380959/
https://www.ncbi.nlm.nih.gov/pubmed/28378857
http://dx.doi.org/10.1038/srep46086