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USP9X regulates centrosome duplication and promotes breast carcinogenesis

Defective centrosome duplication is implicated in microcephaly and primordial dwarfism as well as various ciliopathies and cancers. Yet, how the centrosome biogenesis is regulated remains poorly understood. Here we report that the X-linked deubiquitinase USP9X is physically associated with centriola...

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Detalles Bibliográficos
Autores principales: Li, Xin, Song, Nan, Liu, Ling, Liu, Xinhua, Ding, Xiang, Song, Xin, Yang, Shangda, Shan, Lin, Zhou, Xing, Su, Dongxue, Wang, Yue, Zhang, Qi, Cao, Cheng, Ma, Shuai, Yu, Na, Yang, Fuquan, Wang, Yan, Yao, Zhi, Shang, Yongfeng, Shi, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5380967/
https://www.ncbi.nlm.nih.gov/pubmed/28361952
http://dx.doi.org/10.1038/ncomms14866