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Polysulfides (H(2)S(n)) produced from the interaction of hydrogen sulfide (H(2)S) and nitric oxide (NO) activate TRPA1 channels
Hydrogen sulfide (H(2)S) exerts synergistic effects with another gaseous signaling molecule nitric oxide (NO) on ion channels and vasculature. However, the mechanism of the synergy is not well understood. Here, we show that the interaction between H(2)S and NO generates polysulfides (H(2)S(n)), whic...
Autores principales: | Miyamoto, Ryo, Koike, Shin, Takano, Yoko, Shibuya, Norihiro, Kimura, Yuka, Hanaoka, Kenjiro, Urano, Yasuteru, Ogasawara, Yuki, Kimura, Hideo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5380989/ https://www.ncbi.nlm.nih.gov/pubmed/28378773 http://dx.doi.org/10.1038/srep45995 |
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