Non-photonic sensing of membrane-delimited reactive species with a Na(+) channel protein containing selenocysteine

Photonic experiments are of key importance in life sciences but light-induced side effects are serious confounding factors. Here we introduce roNa(V)2, an engineered voltage-gated Na(+) channel harboring a selenocysteine in its inactivation motif, as a non-photonic, sensitive, gateable, and reversib...

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Detalles Bibliográficos
Autores principales: Ojha, Navin K., Leipold, Enrico, Schönherr, Roland, Hoshi, Toshinori, Heinemann, Stefan H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5381000/
https://www.ncbi.nlm.nih.gov/pubmed/28378799
http://dx.doi.org/10.1038/srep46003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5381000/
https://www.ncbi.nlm.nih.gov/pubmed/28378799
http://dx.doi.org/10.1038/srep46003

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