Aipl1 is required for cone photoreceptor function and survival through the stability of Pde6c and Gc3 in zebrafish

Genetic mutations in aryl hydrocarbon receptor interacting protein-like 1 (AIPL1) cause photoreceptor degeneration associated with Leber congenital amaurosis 4 (LCA4) in human patients. Here we report retinal phenotypes of a zebrafish aipl1 mutant, gold rush (gosh). In zebrafish, there are two aipl1...

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Detalles Bibliográficos
Autores principales: Iribarne, Maria, Nishiwaki, Yuko, Nakamura, Shohei, Araragi, Masato, Oguri, Eri, Masai, Ichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5381001/
https://www.ncbi.nlm.nih.gov/pubmed/28378769
http://dx.doi.org/10.1038/srep45962

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5381001/
https://www.ncbi.nlm.nih.gov/pubmed/28378769
http://dx.doi.org/10.1038/srep45962

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