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Detection of newly produced T and B lymphocytes by digital PCR in blood stored dry on nylon flocked swabs

BACKGROUND: A normal number of T-cell receptor excision circles (TRECs) and K-deleting recombination excision circles (KRECs) is considered a biomarker for adequate new T- and B-cell production. In newborns, detection of TRECs and KRECs by real time PCR from dried blood spotted on filter paper is us...

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Detalles Bibliográficos
Autores principales: Tessitore, Marion Vaglio, Sottini, Alessandra, Roccaro, Aldo M., Ghidini, Claudia, Bernardi, Simona, Martellosio, Giovanni, Serana, Federico, Imberti, Luisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5381048/
https://www.ncbi.nlm.nih.gov/pubmed/28381232
http://dx.doi.org/10.1186/s12967-017-1169-9